Gastric cancer (GC) is characterized by poor efficacy and modest clinical impact of current therapies, in which apoptosis evasion is relevant.Intracellular calcium homeostasis dysregulation is associated with apoptosis escaping, and aberrant expression of calcium regulator genes could promote GC drug resistance.Since we previously found a Anti-Glar
In the article the questions of expediency of the recovery of the tax benefits on Spoons tax on profit of organizations with the aim of stimulating investment activity of economic entities.Particular attention should be paid to the restoration of investment incentives for income tax; the need to expand the rights of regional and local authorities i
Abstract The northeast of Brazil is characterized by a semiarid climate, in which there is a considerable temporal and spatial variability in the distribution of rainfall.In this region, the occurrence of intense rainfall events (IREs) causes severe damage to the population, given that the rampant urbanization and land use processes make cities mor
The recent spread of Zika virus (ZIKV) and its association with increased rates of Guillain Barre and other neurological disorders as well as congenital defects that include microcephaly has created an urgent need to develop animal models to examine the pathogenesis of the disease and explore the efficacy of potential therapeutics and vaccines.Rece